Putrescine N-methyltransferase

putrescine N-methyltransferase
Identifiers
EC no.2.1.1.53
CAS no.9075-39-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a putrescine N-methyltransferase (EC 2.1.1.53) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + putrescine S-adenosyl-L-homocysteine + N-methylputrescine

Thus, the two substrates of this enzyme are S-adenosyl methionine and putrescine, whereas its two products are S-adenosylhomocysteine and N-methylputrescine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:putrescine N-methyltransferase. This enzyme is also called putrescine methyltransferase. This enzyme participates in alkaloid biosynthesis ii.

This enzyme is important in the synthesis of many plant alkaloids. It evolved from spermidine synthase.