Spermidine synthase

spermidine synthase
Spermidine synthase tetramer, Bacillus subtilis
Identifiers
SymbolSRM
Alt. symbolsSRML1
NCBI gene6723
HGNC11296
OMIM182891
RefSeqNM_003132
UniProtP19623
Other data
EC number2.5.1.16
LocusChr. 1 p36-p22
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StructuresSwiss-model
DomainsInterPro

Spermidine synthase is an enzyme (EC 2.5.1.16) that catalyzes the transfer of the propylamine group from S-adenosylmethioninamine to putrescine in the biosynthesis of spermidine. The systematic name is S-adenosyl 3-(methylthio)propylamine:putrescine 3-aminopropyltransferase and it belongs to the group of aminopropyl transferases. It does not need any cofactors. Most spermidine synthases exist in solution as dimers.