Thiamine monophosphate

Thiamine monophosphate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.007.762
MeSH Thiamine+Monophosphate
UNII
  • InChI=1S/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H Y
    Key: GUGWNSHJDUEHNJ-UHFFFAOYSA-N Y
  • InChI=1/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H
    Key: GUGWNSHJDUEHNJ-UHFFFAOYAK
  • Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCOP(=O)(O)O.[Cl-]
Properties
C12H18N4O4PS+
Molar mass 345.336 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Thiamine monophosphate, also known as ThMP and TMP, is a phosphate ester of thiamine.

It is an intermediate from the hydrolysis of thiamine diphosphate to free thiamine by alkaline phosphatase. The conversion of ThMP to thiamine cannot be facilitated by acid hydrolysis. ThMP is also enzymatically synthesized by thiamine-phosphate pyrophosphorylase, which combines thiazole in its monophosphate form and pyrimidine as a pyrophosphate.

The physiological function of ThMP has not been identified.