The Very Best of TLC: Crazy Sexy Hits

The Very Best of TLC: Crazy Sexy Hits (released digitally as The Best of TLC) is the second greatest hits album by American girl group TLC. It was released exclusively in the United Kingdom on August 20, 2007, by Sony BMG. Having a similar track listing to that of the group's first compilation, Now & Forever: The Hits (2003), the album contains TLC's most successful singles from four of their studio albums, which have been credited to many of the group's producers such as Dallas Austin and Kenneth "Babyface" Edmonds.

The album received mostly positive reaction from music critics, with many expressing admiration for the compilation. However, the album was a commercial disappointment, peaking at number 57 on the UK Albums Chart. This position, however, was higher than Now & Forever: The Hits's performance in the past. In 2013, the album, along with most of their other compilations, were removed from the iTunes Store after the release of their latest greatest hits collection 20.