The 78

The 78 is a plot of land in Chicago from Roosevelt Road south to 16th Street and Clark Street west to the Chicago River that is not developed as of June 2025. The plot of land gained its name from a proposal in 2018, not built, that consisted of several office and residential towers, high-rises, and include a riverwalk. Related Midwest, owner of the site, would develop the site, and Skidmore, Owings & Merrill designed the project's master plan. Related Midwest acquired the land in 2016.

The 78 was to include a $1.2 billion research center called the Discovery Partners Institute, which operated by the University of Illinois. That project may be built further to the south in Chicago.

In April 2019, the Chicago City Council approved The 78 development, including a tax increment financing agreement. It was not built.

In 2021, it was proposed to put a Rivers Casino in The 78 as part of the Chicago Casino Proposals, but the city selected a site in the River West district near the intersection of Chicago Avenue and Halsted Street for a casino and entertainment complex.

In June 2025, the owner of the Chicago Fire FC soccer team has proposed to build a stadium for soccer games on the site.