TXK (gene)

TXK
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DM0
Identifiers
Aliases	TXK, BTKL, PSCTK5, PTK4, RLK, TKL, TXK tyrosine kinase
External IDs	OMIM: 600058; MGI: 102960; HomoloGene: 2497; GeneCards: TXK; OMA:TXK - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	48,134,250 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	72,910,120 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; testicle; ; spleen; ; lymph node; ; appendix; ; right uterine tube; ; bone marrow cells; ; right lobe of liver; ; upper lobe of left lung;
	Top expressed in
	thymus; ; blood; ; lymph node; ; morula; ; pharynx; ; mesenteric lymph nodes; ; spleen; ; subcutaneous adipose tissue; ; granulocyte; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; DNA binding; protein kinase activity; DNA-binding transcription activator activity, RNA polymerase II-specific; kinase activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; protein tyrosine kinase activity; signaling receptor binding; ATP binding; non-membrane spanning protein tyrosine kinase activity;
Cellular component	cytoplasm; membrane; extrinsic component of cytoplasmic side of plasma membrane; plasma membrane; nucleus;
Biological process	cell differentiation; regulation of transcription, DNA-templated; adaptive immune response; phosphorylation; tissue regeneration; transmembrane receptor protein tyrosine kinase signaling pathway; immune system process; regulation of transcription by RNA polymerase II; cytokine production; positive regulation of interferon-gamma-mediated signaling pathway; positive regulation of interferon-gamma production; activation of phospholipase C activity; transcription, DNA-templated; protein phosphorylation; regulation of cell population proliferation; peptidyl-tyrosine autophosphorylation; integrin-mediated signaling pathway; protein autophosphorylation; regulation of platelet activation; T cell receptor signaling pathway; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7294
	22165
	ENSG00000074966
	ENSMUSG00000054892
	P42681
	P42682
	NM_003328
	NM_001122754; NM_001289494; NM_001289495; NM_013698
	NP_003319
	NP_001116226; NP_001276423; NP_001276424; NP_038726
	Wikidata
View/Edit Human	View/Edit Mouse

Tyrosine-protein kinase TXK is an enzyme that in humans is encoded by the TXK gene.