Spätzle (gene)

Spätzle (gene)
Identifiers
OrganismDrosophila melanogaster
Symbolspz
UniProtP48607
Search for
StructuresSwiss-model
DomainsInterPro
Spätzle
Identifiers
SymbolSpaetzle
PfamPF16077
InterProIPR032104
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Spätzle or spaetzle (German for a type of noodle) is an evolutionarily-conserved arthropod protein first identified in Drosophila melanogaster. It plays a role in embryonic development and in the insect innate immune response. The name was coined by the Nobel laureate Christiane Nüsslein-Volhard after the Spätzle noodle-like form of homozygous mutant fly larvae.