Seribantumab

Seribantumab
Monoclonal antibody
Type?
SourceHuman
TargetHER3
Clinical data
Other namesMM-121
ATC code
  • none
Identifiers
CAS Number
IUPHAR/BPS
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6340H9810N1690O1986S52
Molar mass143151.18 g·mol−1

Seribantumab (INN; development code MM-121) is a monoclonal antibody designed for the treatment of cancer. It binds to extracellular domain of HER3 blocking NRG1 binding and thereby preventing the activation of the receptor.

This drug was developed by Sanofi/Merrimack Pharmaceuticals, Inc.