| Office | Name | Date |
|---|
| First Lord of the Treasury | William Cavendish-Bentinck, 3rd Duke of Portland | 31 March 1807 – 4 October 1809 |
Chancellor of the Exchequer
Chancellor of the Duchy of Lancaster | Spencer Perceval | 26 March 1807
30 March 1807 – |
| Secretaries to the Treasury | Senior Secretary | Hon. Henry Wellesley | 1 April 1807 – 21 March 1809 |
| Charles Arbuthnot | 5 April 1809 |
| Junior Secretary | William Huskisson | 1 April 1807 |
| Junior Lords of the Treasury | William Cavendish-Scott-Bentinck, Marquess of Titchfield | 31 March 1807 – 16 September 1807 |
| Hon. William Eliot | 31 March 1807 |
| William Sturges Bourne | 31 March 1807 – 16 September 1807 |
| John Foster | 16 September 1807 |
| Hon. Richard Ryder | 16 September 1807 – 2 December 1807 |
| Hon. William Brodrick | 2 December 1807 |
| Snowdon Barne | 2 December 1807 |
| Lord President of the Council | John Pratt, 1st Earl Camden | 26 March 1807 |
| Lord Chancellor | John Scott, 1st Baron Eldon | 1 April 1807 |
| Home Secretary | Robert Jenkinson, Baron Hawkesbury | 25 March 1807 |
| Under-Secretary of State for the Home Department | Charles Watkin Williams-Wynn | continued in office |
| Charles Jenkinson | November 1807 |
| Secretary of State for Foreign Affairs | George Canning | 25 March 1807 |
| Under-Secretary of State for Foreign Affairs | James Harris, Viscount FitzHarris | March 1807 |
| Charles Bagot | August 1807 |
President of the Board of Trade
Master of the Mint | Henry Bathurst, 3rd Earl Bathurst | 26 March 1807
25 April 1807 |
| Vice-President of the Board of Trade | George Rose | March 1807 |
| Secretary of State for War and the Colonies | Robert Stewart, Viscount Castlereagh | 25 March 1807 |
| Under-Secretary of State for War and the Colonies | Edward Cooke | 1807 |
| Charles Stewart | 1807 |
| Frederick Robinson | 1809 |
| President of the Board of Control | Robert Saunders-Dundas | 6 April 1807 |
| Dudley Ryder, 1st Earl of Harrowby | 17 July 1809 |
| Secretary to the Board of Control | George Peter Holford | continued in office |
| First Lord of the Admiralty | Henry Phipps, 2nd Baron Mulgrave | 4 April 1807 |
| First Secretary to the Admiralty | William Wellesley-Pole | 1807 |
| Civil Lords of the Admiralty | Robert Plumer Ward | 6 April 1807 |
| Henry John Temple, 3rd Viscount Palmerston | 6 April 1807 |
| James Buller | 6 April 1807 |
| Lord Privy Seal | John Fane, 10th Earl of Westmorland | 25 March 1807 |
| Master-General of the Ordnance | John Pitt, 2nd Earl of Chatham | 4 April 1807 |
| Lieutenant-General of the Ordnance | Sir Thomas Trigge | continued in office |
| Treasurer of the Ordnance | Joseph Hunt | continued in office |
| Surveyor-General of the Ordnance | James Murray Hadden | continued in office |
| Clerk of the Ordnance | William Wellesley-Pole | 7 April 1807 |
| Cropley Ashley-Cooper | 29 July 1807 |
| Clerk of the Deliveries of the Ordnance |
Cropley Ashley-Cooper | 7 April 1807 |
| Thomas Thoroton | 29 July 1807 |
| Storekeeper of the Ordnance | Mark Singleton | 7 April 1807 |
| Treasurer of the Navy | George Rose | 15 April 1807 |
| Secretary at War | Sir James Pulteney, 7th Baronet | 30 March 1807 |
| Lord Granville Leveson-Gower | 27 June 1809 |
| Paymaster of the Forces | Charles Long | April 1807 |
| Lord Charles Henry Somerset | April 1807 |
| Postmaster General | Thomas Pelham, 2nd Earl of Chichester | 1807 |
| John Montagu, 5th Earl of Sandwich | 1807 |
| Surveyor General of Woods, Forests, Parks, and Chases | Sylvester Douglas, 1st Baron Glenbervie | 1807 |
| Ministers without Portfolio | William Cavendish-Bentinck, 3rd Duke of Portland | 4 October 1809 – 30 October 1809 |
| Dudley Ryder, 1st Earl of Harrowby | November 1809 – June 1812 |
| John Pratt, 1st Earl Camden | 8 April 1812 – June 1812 |
| Lord Lieutenant of Ireland | Charles Lennox, 4th Duke of Richmond | April 1807 |
| Chief Secretary for Ireland | Sir Arthur Wellesley | April 1807 |
| Robert Saunders-Dundas | April 1809 |
| Attorney General | Sir Vicary Gibbs | April 1807 |
| Solicitor General | Sir Thomas Plumer | April 1807 |
| Judge Advocate General | Nathaniel Bond | 8 March 1806 |
| Richard Ryder | 4 December 1807 |
| Lord Advocate | Archibald Colquhoun | 1807 |
| Solicitor General for Scotland | David Boyle | 1807 |
| Attorney General for Ireland | William Saurin | 15 May 1807 |
| Solicitor General for Ireland | Charles Kendal Bushe | continued in office |
| Lord Steward of the Household | Heneage Finch, 4th Earl of Aylesford | continued in office |
| Treasurer of the Household | James Stopford, Viscount Stopford | 1807 |
| Comptroller of the Household | Lord George Thynne | continued in office |
| Lord Chamberlain of the Household | George Legge, 3rd Earl of Dartmouth | continued in office |
| Vice-Chamberlain of the Household | Lord John Thynne | continued in office |
| Master of the Horse | James Graham, 3rd Duke of Montrose | 1807 |
| Master of the Buckhounds | Charles Cornwallis, 2nd Marquess Cornwallis | continued in office |
| Captain of the Gentlemen Pensioners | St Andrew St John, 14th Baron St John of Bletso | continued in office |
| Richard Edgcumbe, 2nd Earl of Mount Edgcumbe | 2 March 1808 |
| Captain of the Yeomen of the Guard | George Parker, 4th Earl of Macclesfield | continued in office |