The Second Army Corps was a unit of the United States Army raised for the Spanish–American War.
A defining event of the Spanish–American War was the typhoid fever epidemic of July to November 1898. The Army consequently undertook a series of mass-retreats and attempted evasions. The Typhoid Board concluded that only one of the five army corps stricken with epidemic typhoid succeeded in suppressing the disease actively, the 2nd Army Corps. In the wake of two fruitless relocations and months of casualties, commanders finally managed to impose an effective latrine-policy. A three-part strategy of draconian defecation-management, mass-disinfection, and flight received the Typhoid Board's imprimatur as the principal, recommended method for suppressing existing epidemics.