SC-17599

SC-17599
Clinical data
Other names	SC-17599; 17α-Acetoxy-6-dimethylaminomethyl-21-fluoro-3-ethoxypregna-3,5-dien-20-one; [(8R,9S,10R,13S,14S,17R)-6-(dimethylaminomethyl)-3-ethoxy-17-(2-fluoroacetyl)-10,13-dimethyl-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate
Legal status
Legal status	In general: legal;
Identifiers
	IUPAC name 6-[(dimethylamino)methyl]-3-ethoxy-21-fluoro-20-oxopregna-3,5-dien-17-yl acetate;
CAS Number	23775-92-0;
PubChem CID	10436424;
ChemSpider	8611848 ;
UNII	J9BXL4PC5V;
CompTox Dashboard (EPA)	DTXSID301018437 ;
Chemical and physical data
Formula	C28H42FNO4
Molar mass	475.645 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES FCC(=O)[C@@]1(OC(=O)C)CC[C@H]2[C@H]4[C@H](CC[C@]12C)[C@@]3(C(\C=C(\OCC)CC3)=C(\CN(C)C)C4)C;
	InChI InChI=1S/C28H42FNO4/c1-7-33-20-8-11-26(3)22-9-12-27(4)23(10-13-28(27,25(32)16-29)34-18(2)31)21(22)14-19(17-30(5)6)24(26)15-20/h15,21-23H,7-14,16-17H2,1-6H3/t21-,22+,23+,26-,27+,28+/m1/s1 ; Key:ZPVGJKVIJYUOCI-ORZTVLAMSA-N ;
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SC-17599 is a steroid derivative drug discovered in 1968 which acts as a selective μ-opioid receptor agonist, with little or no affinity for the δ-opioid or κ-opioid receptors. It is an active analgesic in vivo, more potent than codeine or pethidine but slightly less potent than morphine, and produces similar effects to morphine in animals but with less sedation