Propiram

Propiram
Clinical data
Routes of; administration	By mouth, injected
ATC code	none;
Legal status
Legal status	AU: S8 (Controlled drug); BR: Class A2 (Narcotic drugs); CA: Schedule I; DE: Anlage II (Authorized trade only, not prescriptible); US: Schedule I;
Pharmacokinetic data
Bioavailability	97%
Elimination half-life	5.2 hours
Identifiers
	IUPAC name N-(1-Methyl-2-piperidin-1-ylethyl)-N-pyridin-2-ylpropanamide;
CAS Number	15686-91-6 ;
PubChem CID	26216;
ChemSpider	24426 ;
UNII	WT6247U6PX;
CompTox Dashboard (EPA)	DTXSID1023522 ;
ECHA InfoCard	100.036.144
Chemical and physical data
Formula	C16H25N3O
Molar mass	275.396 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N(c1ncccc1)C(CN2CCCCC2)C)CC;
	InChI InChI=1S/C16H25N3O/c1-3-16(20)19(15-9-5-6-10-17-15)14(2)13-18-11-7-4-8-12-18/h5-6,9-10,14H,3-4,7-8,11-13H2,1-2H3 ; Key:ZBAFFZBKCMWUHM-UHFFFAOYSA-N ;
	(what is this?) (verify)

Propiram (Algeril, Dirame, Bay 4503) is a partial μ-opioid receptor agonist and weak μ antagonist analgesic from the ampromide family of drugs related to other drugs such as phenampromide and diampromide. It was invented in 1963 in the United Kingdom by Bayer but was not widely marketed, although it saw some limited clinical use, especially in dentistry. Propiram reached Phase III clinical trials in the United States and Canada.

Clinical data

Routes of administration	By mouth, injected
ATC code	none
Legal status
Legal status	AU: S8 (Controlled drug) BR: Class A2 (Narcotic drugs) CA: Schedule I DE: Anlage II (Authorized trade only, not prescriptible) US: Schedule I
Pharmacokinetic data
Bioavailability	97%
Elimination half-life	5.2 hours
Identifiers
IUPAC name N-(1-Methyl-2-piperidin-1-ylethyl)-N-pyridin-2-ylpropanamide
CAS Number	15686-91-6^N
PubChem CID	26216
ChemSpider	24426^Y
UNII	WT6247U6PX
CompTox Dashboard (EPA)	DTXSID1023522
ECHA InfoCard	100.036.144
Chemical and physical data
Formula	C₁₆H₂₅N₃O
Molar mass	275.396 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(N(c1ncccc1)C(CN2CCCCC2)C)CC
InChI InChI=1S/C16H25N3O/c1-3-16(20)19(15-9-5-6-10-17-15)14(2)13-18-11-7-4-8-12-18/h5-6,9-10,14H,3-4,7-8,11-13H2,1-2H3^Y Key:ZBAFFZBKCMWUHM-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)