Pentosan polysulfate

Pentosan polysulfate
Clinical data
Trade names	Elmiron, Zycosan
Other names	PPS, (1->4)-β-Xylan 2,3-bis(hydrogen sulfate) with a 4 O-methyl-α-D-glucuronate
AHFS/Drugs.com	Monograph
License data	US DailyMed: pentosan polysulfate;
Routes of; administration	By mouth, intramuscular
ATC code	C05BA04 (WHO) G04BX15 (WHO), QC05BA04 (WHO), QG04BX15 (WHO) QM01AX90 (WHO);
Legal status
Legal status	US: ℞-only;
Pharmacokinetic data
Excretion	Feces, urine
Identifiers
CAS Number	37300-21-3 ; as sodium: 140207-93-8;
PubChem CID	37720;
DrugBank	DB00686;
ChemSpider	34595 ;
UNII	F59P8B75R4; as sodium: 914032762Y;
KEGG	as sodium: D05428;
ChEMBL	ChEMBL4073796; as sodium: ChEMBL1201516;
CompTox Dashboard (EPA)	DTXSID10190764 ;
Chemical and physical data
Formula	C10H18O21S4
Molar mass	602.47 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O[C@@H]1CO[C@@H](O[C@@H]2CO[C@@H](O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]1OS(O)(=O)=O;
	InChI InChI=1S/C10H18O21S4/c11-3-1-26-10(8(31-35(22,23)24)5(3)28-32(13,14)15)27-4-2-25-9(12)7(30-34(19,20)21)6(4)29-33(16,17)18/h3-12H,1-2H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)/t3-,4-,5+,6+,7-,8-,9-,10+/m1/s1; Key:FCCNSUIJIOOXEZ-SJYYZXOBSA-N;
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Pentosan polysulfate, sold under the brand name Elmiron among others, is a medication used for interstitial cystitis. Evidence of benefit; however, is mixed as of 2024. It is recommended that the medication be stopped if there is no improvement within 6 months. It was approved for medical use in the United States in 1996.