Penpulimab

Penpulimab
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetPD-1
Clinical data
Other namesAK105, penpulimab-kcqx
License data
Routes of
administration
Intravenous
Drug classAntineoplastic agent
ATC code
  • None
Legal status
Legal status
  • US: ℞-only
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem SID
IUPHAR/BPS
DrugBank
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC6434H9922N1718O2012S46
Molar mass145008.92 g·mol−1

Penpulimab is a humanized monoclonal antibody used for the treatment of cancer. It targets the programmed cell death protein 1 (PD-1) receptor.

Penpulimab was approved for medical use in China in August 2021, and in the United States in April 2025.