NFEPP

NFEPP
Clinical data
Drug classOpioid
Legal status
Legal status
Identifiers
  • N-(3-Fluoro-1-phenethylpiperidin-4-yl)-N-phenylpropionamide
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H27FN2O
Molar mass354.469 g·mol−1
3D model (JSmol)
  • CCC(=O)N(c1ccccc1)[C@H]2CCN(C[C@H]2F)CCc3ccccc3
  • InChI=1S/C22H27FN2O/c1-2-22(26)25(19-11-7-4-8-12-19)21-14-16-24(17-20(21)23)15-13-18-9-5-3-6-10-18/h3-12,20-21H,2,13-17H2,1H3/t20-,21+/m1/s1
  • Key:DMCQJJAWMFBPOX-RTWAWAEBSA-N

NFEPP (N-(3-fluoro-1-phenethylpiperidin-4-yl)-N-phenylpropionamide) is an analgesic opioid chemical, similar in structure to fentanyl, designed in 2016 by Spahn et al. from Free University of Berlin to avoid the standard negative side effects of opiates, including opioid overdose, by only targeting inflamed tissue.