MAFF (gene)

MAFF
Identifiers
Aliases	MAFF, U-MAF, hMafF, MAF bZIP transcription factor F
External IDs	OMIM: 604877; MGI: 96910; HomoloGene: 7825; GeneCards: MAFF; OMA:MAFF - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	38,216,507 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,243,276 bp
RNA expression pattern
	Top expressed in
	amniotic fluid; ; mucosa of paranasal sinus; ; mucosa of urinary bladder; ; cartilage tissue; ; pericardium; ; vena cava; ; pancreatic ductal cell; ; buccal mucosa cell; ; parotid gland; ; saphenous vein;
	Top expressed in
	aortic valve; ; decidua; ; ascending aorta; ; endothelial cell of lymphatic vessel; ; female urethra; ; esophagus; ; lip; ; yolk sac; ; left lung lobe; ; tail of embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	mitochondrion; nucleoplasm; nucleus;
Biological process	skeletal muscle cell differentiation; regulation of epidermal cell differentiation; blood coagulation; in utero embryonic development; regulation of transcription, DNA-templated; transcription by RNA polymerase II; birth; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	23764
	17133
	ENSG00000185022
	ENSMUSG00000042622
	Q9ULX9
	O54791
	NM_152878; NM_001161572; NM_001161573; NM_001161574; NM_012323
	NM_010755; NM_001304830; NM_001304831; NM_001304832
	NP_001155044; NP_001155045; NP_001155046; NP_036455
	NP_001291759; NP_001291760; NP_001291761; NP_034885
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor MafF is a bZip Maf transcription factor protein that in humans is encoded by the MAFF gene.

MafF is one of the small Maf proteins, which are basic region and leucine zipper (bZIP)-type transcription factors. The HUGO Gene Nomenclature Committee-approved gene name of MAFF is “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F”.