| Country (State/Province) |
City |
Airport |
Notes |
Refs |
| Aruba | Oranjestad | Queen Beatrix International Airport | | |
| Bahamas | Freeport | Grand Bahama International Airport | Terminated | |
| Nassau | Lynden Pindling International Airport | Terminated | |
| San Salvador Island | San Salvador Airport | Terminated | |
| Cayman Islands | Grand Cayman | Owen Roberts International Airport | Terminated | |
| Colombia | Armenia | El Edén International Airport | | |
| Barranquilla | Ernesto Cortissoz International Airport | | |
| Bogotá | El Dorado International Airport | | |
| Bucaramanga | Palonegro International Airport | | |
| Cali | Alfonso Bonilla Aragón International Airport | | |
| Cartagena | Rafael Núñez International Airport | | |
| Medellín | José María Córdova International Airport | | |
| Costa Rica | San José | Juan Santamaría International Airport | | |
| Cuba | Havana | Jose Marti International Airport | Terminated | |
| Dominican Republic | Punta Cana | Punta Cana International Airport | | |
| Santiago | Cibao International Airport | | |
| Santo Domingo | Las Américas International Airport | | |
| Ecuador | Guayaquil | José Joaquín de Olmedo International Airport | | |
| El Salvador | San Luis Talpa | Monseñor Óscar Arnulfo Romero International Airport | | |
| Guatemala | Guatemala City | La Aurora International Airport | | |
| Haiti | Cap-Haïtien | Cap-Haïtien International Airport | | |
| Port-au-Prince | Toussaint Louverture International Airport | | |
| Honduras | San Pedro Sula | Ramón Villeda Morales International Airport | | |
| Tegucigalpa | Comayagua International Airport | | |
| Jamaica | Kingston | Norman Manley International Airport | | |
| Montego Bay | Sangster International Airport | | |
| Mexico (Baja California Sur) | San José del Cabo | Los Cabos International Airport | Terminated | |
| Mexico (Jalisco) | Puerto Vallarta | Licenciado Gustavo Díaz Ordaz International Airport | Terminated | |
| Mexico (Quintana Roo) | Cancún | Cancún International Airport | | |
| Tulum | Tulum International Airport | | |
| Mexico (State of Mexico) | Toluca | Lic. Adolfo López Mateos International Airport | Terminated | |
| Nicaragua | Managua | Augusto C. Sandino International Airport | Seasonal | |
| Panama | Panama City | Tocumen International Airport | Terminated | |
| Peru | Lima | Jorge Chávez International Airport | Seasonal | |
| Sint Maarten | Philipsburg | Princess Juliana International Airport | | |
| Trinidad and Tobago | Port-of-Spain | Piarco International Airport | Terminated | |
| Turks and Caicos Islands | Grand Turk Island | JAGS McCartney International Airport | Terminated | |
| Providenciales | Providenciales International Airport | Terminated | |
| United States (Alabama) | Birmingham | Birmingham–Shuttlesworth International Airport | | |
| United States (Arizona) | Phoenix | Phoenix Sky Harbor International Airport | | |
| Phoenix–Mesa Gateway Airport | Terminated | |
| United States (California) | Burbank | Hollywood Burbank Airport | | |
| Los Angeles | Los Angeles International Airport | | |
| Oakland | Oakland International Airport | | |
| Santa Ana | John Wayne Airport | | |
| Sacramento | Sacramento International Airport | | |
| San Diego | San Diego International Airport | | |
| San Jose | San Jose International Airport | | |
| United States (Colorado) | Denver | Denver International Airport | Terminated | |
| United States (Connecticut) | Hartford | Bradley International Airport | | |
| United States (District of Columbia) | Washington, D.C. | Ronald Reagan Washington National Airport | Terminated | |
| United States (Florida) | Fort Lauderdale | Fort Lauderdale–Hollywood International Airport | Base | |
| Fort Myers | Southwest Florida International Airport | | |
| Jacksonville | Jacksonville International Airport | Terminated | |
| Miami | Miami International Airport | Base | |
| Orlando | Orlando International Airport | Base | |
| Pensacola | Pensacola International Airport | | |
| Tampa | Tampa International Airport | | |
| West Palm Beach | Palm Beach International Airport | | |
| United States (Georgia) | Atlanta | Hartsfield–Jackson Atlanta International Airport | Base | |
| Savannah | Savannah/Hilton Head International Airport | Begins August 14, 2025 | |
| United States (Idaho) | Boise | Boise Airport | | |
| United States (Illinois) | Chicago | O'Hare International Airport | Base | |
| United States (Indiana) | Indianapolis | Indianapolis International Airport | | |
| United States (Kentucky) | Louisville | Louisville Muhammad Ali International Airport | | |
| United States (Louisiana) | New Orleans | Louis Armstrong New Orleans International Airport | | |
| United States (Maryland) | Baltimore | Baltimore/Washington International Airport | | |
| United States (Massachusetts) | Boston | Logan International Airport | | |
| United States (Michigan) | Detroit | Detroit Metropolitan Wayne County Airport | Base | |
| United States (Minnesota) | Minneapolis/Saint Paul | Minneapolis–Saint Paul International Airport | | |
| United States (Missouri) | Kansas City | Kansas City International Airport | | |
| St. Louis | St. Louis Lambert International Airport | | |
| United States (Nevada) | Las Vegas | Harry Reid International Airport | Base | |
| Reno/Tahoe | Reno–Tahoe International Airport | | |
| United States (New Hampshire) | Manchester | Manchester–Boston Regional Airport | Terminated | |
| United States (New Jersey) | Atlantic City | Atlantic City International Airport | | |
| Newark | Newark Liberty International Airport | Base | |
| United States (New York) | Islip | Long Island MacArthur Airport | Terminated | |
| New York City | LaGuardia Airport | | |
| Niagara Falls | Niagara Falls International Airport | Terminated | |
| Plattsburgh | Plattsburgh International Airport | Terminated | |
| Rochester | Greater Rochester International Airport | | |
| United States (North Carolina) | Asheville | Asheville Regional Airport | Terminated | |
| Charlotte | Charlotte Douglas International Airport | | |
| Greensboro/High Point | Piedmont Triad International Airport | Terminated | |
| Raleigh/Durham | Raleigh–Durham International Airport | | |
| United States (Ohio) | Akron/Canton | Akron–Canton Airport | Terminated | |
| Cleveland | Cleveland Hopkins International Airport | | |
| Columbus | John Glenn Columbus International Airport | | |
| United States (Oregon) | Portland | Portland International Airport | | |
| United States (Pennsylvania) | Latrobe | Arnold Palmer Regional Airport | | |
| Philadelphia | Philadelphia International Airport | | |
| Pittsburgh | Pittsburgh International Airport | | |
| United States (Puerto Rico) | Aguadilla | Rafael Hernández Airport | Seasonal | |
| Ponce | Mercedita International Airport | Seasonal | |
| San Juan | Luis Muñoz Marín International Airport | | |
| United States (Rhode Island) | Providence | Rhode Island T. F. Green International Airport | Terminated | |
| United States (South Carolina) | Charleston | Charleston International Airport | | |
| Columbia | Columbia Metropolitan Airport | | |
| Myrtle Beach | Myrtle Beach International Airport | | |
| United States (Tennessee) | Memphis | Memphis International Airport | | |
| Nashville | Nashville International Airport | | |
| United States (Texas) | Austin | Austin–Bergstrom International Airport | | |
| Dallas/Fort Worth | Dallas Fort Worth International Airport | Base | |
| Houston | George Bush Intercontinental Airport | Base | |
| San Antonio | San Antonio International Airport | | |
| United States (U.S. Virgin Islands) | St. Thomas | Cyril E. King Airport | | |
| St. Croix | Henry E. Rohlsen Airport | | |
| United States (Utah) | Salt Lake City | Salt Lake City International Airport | | |
| United States (Virginia) | Norfolk | Norfolk International Airport | | |
| Richmond | Richmond International Airport | | |
| United States (Washington) | Seattle/Tacoma | Seattle–Tacoma International Airport | | |
| United States (Wisconsin) | Milwaukee | Milwaukee Mitchell International Airport | | |
| United States (West Virginia) | Charleston | Yeager Airport | Terminated | |