Lhermitte–Duclos disease

Lhermitte-Duclos disease (LDD)
Other namesDysplastic gangliocytoma of the cerebellum (DGC)
Lhermitte-Duclos disease histology
SpecialtyNeuro-oncology

Lhermitte–Duclos disease (LDD) (English: /ˌlɛərˈmtˌdˈkl/), also called dysplastic gangliocytoma of the cerebellum (DGC), is a rare, slowly growing tumor of the cerebellum, a gangliocytoma sometimes considered to be a hamartoma, characterized by diffuse hypertrophy of the granular layer of the cerebellum. It is often associated with Cowden syndrome. It was described by Jacques Jean Lhermitte and P. Duclos in 1920.