LARS2

LARS2
Identifiers
Aliases	LARS2, LEURS, PRLTS4, mtLeuRS, leucyl-tRNA synthetase 2, mitochondrial, HLASA
External IDs	OMIM: 604544; MGI: 2142973; HomoloGene: 6526; GeneCards: LARS2; OMA:LARS2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	45,554,726 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	123,291,731 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; oocyte; ; secondary oocyte; ; Brodmann area 23; ; mucosa of transverse colon; ; kidney tubule; ; caudate nucleus; ; retinal pigment epithelium; ; prefrontal cortex; ; ganglionic eminence;
	Top expressed in
	zygote; ; yolk sac; ; lip; ; superior frontal gyrus; ; spermatocyte; ; muscle of thigh; ; tail of embryo; ; ventricular zone; ; genital tubercle; ; neural tube;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	aminoacyl-tRNA ligase activity; nucleotide binding; ligase activity; ATP binding; aminoacyl-tRNA editing activity; leucine-tRNA ligase activity;
Cellular component	mitochondrial matrix; mitochondrion;
Biological process	tRNA aminoacylation for protein translation; protein biosynthesis; leucyl-tRNA aminoacylation; mitochondrial translation; aminoacyl-tRNA metabolism involved in translational fidelity;
	Sources:Amigo / QuickGO
Orthologs
	23395
	102436
	ENSG00000011376
	ENSMUSG00000035202
	Q15031
	Q8VDC0
	NM_015340; NM_001368263
	NM_153168; NM_001348167; NM_001348168
	NP_056155; NP_001355192
	NP_694808; NP_001335096; NP_001335097
	Wikidata
View/Edit Human	View/Edit Mouse

Probable leucyl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the LARS2 gene.

This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.