IBMX

IBMX
Names
	IUPAC name 1-Methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
	Other names 3-Isobutyl-1-methylxanthine
Identifiers
CAS Number	28822-58-4 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:34795 ;
ChEMBL	ChEMBL275084 ;
ChemSpider	3627 ;
DrugBank	DB07954 ;
ECHA InfoCard	100.044.767
IUPHAR/BPS	388;
KEGG	C13708 ;
PubChem CID	3758;
UNII	TBT296U68M ;
CompTox Dashboard (EPA)	DTXSID0040549 ;
	InChI InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) Key: APIXJSLKIYYUKG-UHFFFAOYSA-N ; InChI=1/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) Key: APIXJSLKIYYUKG-UHFFFAOYAL;
	SMILES CC(C)Cn1c2c(c(=O)n(c1=O)C)[nH]cn2;
Properties
Chemical formula	C10H14N4O2
Molar mass	222.3 g/mol
Appearance	White solid
Melting point	199 to 201 °C (390 to 394 °F; 472 to 474 K)
Solubility	Soluble in ethanol, DMSO, and methanol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

IBMX (3-isobutyl-1-methylxanthine), like other methylxanthine derivatives, is both a:

competitive non-selective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNFα and leukotriene synthesis, and reduces inflammation and innate immunity, and
nonselective adenosine receptor antagonist.

As a phosphodiesterase inhibitor, IBMX has IC₅₀ = 2–50 μM and does not inhibit PDE8 or PDE9.