Hypothalamospinal tract

The hypothalamospinal tract is an unmyelinated non-decussated descending nerve tract that arises in the hypothalamus and projects to the brainstem and spinal cord to synapse with pre-ganglionic autonomic (both sympathetic and parasympathetic) neurons.

The direct autonomic projections of the hypothalamospinal tract represent a minority of the autonomic output of the hypothalamus; most is thought to project to various relay structures.