Hudepohl Brewing Company is a brewery established in Cincinnati, Ohio in 1885 by founder Ludwig Hudepohl II. Hudepohl was the son of Ludwig Hudepohl who emigrated from Malgarten, Kingdom of Hannover, in 1838. Ludwig II had worked in the surgical tool business before starting his brewery. Hudepohl combined with Schoenling Brewing Company in 1986. Today, the Hudepohl-Schoenling Brewing Company is a wholly owned subsidiary of Christian Moerlein Brewing Company.
The brewery name is also said to be the origin of the "Who Dey" chant done by fans of the Cincinnati Bengals. The slogan went on to be produced on special edition cans of "Hu-Dey" beer for the various Super Bowl runs of the Bengals in 1981, 1989, and most recently 2022.