HR (gene)

HR
Identifiers
Aliases	HR, ALUNC, AU, HSA277165, HYPT4, MUHH, MUHH1, hair growth associated, lysine demethylase and nuclear receptor corepressor, HR lysine demethylase and nuclear receptor corepressor
External IDs	OMIM: 602302; MGI: 96223; HomoloGene: 3774; GeneCards: HR; OMA:HR - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	22,133,384 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	70,810,988 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; skin of leg; ; right hemisphere of cerebellum; ; mucosa of transverse colon; ; vulva; ; right frontal lobe; ; nipple; ; sural nerve; ; prefrontal cortex; ; parotid gland;
	Top expressed in
	lip; ; hair bulb; ; muscle of thigh; ; Epithelium of large intestine; ; inner root sheath; ; esophagus; ; triceps brachii muscle; ; epithelium of rectum; ; skin of back; ; inner enamel epithelium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; oxidoreductase activity; transcription corepressor activity; metal ion binding; transcription cis-regulatory region binding; chromatin DNA binding; histone H3-methyl-lysine-9 demethylase activity;
Cellular component	nuclear body; nucleoplasm; chromatin; nucleus;
Biological process	negative regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription, DNA-templated; histone H3-K9 demethylation;
	Sources:Amigo / QuickGO
Orthologs
	55806
	15460
	ENSG00000168453
	ENSMUSG00000022096
	O43593
	Q61645
	NM_005144; NM_018411
	NM_021877; NM_001379479
	NP_005135; NP_060881
	NP_068677; NP_001366408
	Wikidata
View/Edit Human	View/Edit Mouse

HR is a gene encoding Protein hairless.

This gene encodes a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases.