Glutaminase
| glutaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Crystallographic structure of dimeric protein-glutaminase from Chryseobacterium proteolyticum. | |||||||||
| Identifiers | |||||||||
| EC no. | 3.5.1.2 | ||||||||
| CAS no. | 9001-47-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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| Glutaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
probable glutaminase from bacillus subtilis complexed with 6-diazo-5-oxo-ʟ-norleucine | |||||||||
| Identifiers | |||||||||
| Symbol | Glutaminase | ||||||||
| Pfam | PF04960 | ||||||||
| Pfam clan | CL0013 | ||||||||
| InterPro | IPR015868 | ||||||||
| SCOP2 | 1mki / SCOPe / SUPFAM | ||||||||
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Glutaminase (EC 3.5.1.2, glutaminase I, L-glutaminase, glutamine aminohydrolase) is an amidohydrolase enzyme that generates glutamate from glutamine. Glutaminase has tissue-specific isoenzymes. Glutaminase has an important role in glial cells.
Glutaminase catalyzes the following reaction:
It is useful in the food industry, as it converts free glutamine into the umami-tasting free glutamate.