Frovatriptan

Frovatriptan
Clinical data
Trade names	Frova
Other names	6-methylamino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide; (6R)-6-methylamino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide
AHFS/Drugs.com	Monograph
MedlinePlus	a604013
License data	US DailyMed: Frovatriptan;
Pregnancy; category	AU: B3;
Routes of; administration	Oral
ATC code	N02CC07 (WHO) ;
Legal status
Legal status	CA: ℞-only; US: ℞-only;
Pharmacokinetic data
Bioavailability	20–30%
Metabolism	Liver
Elimination half-life	26 hours
Excretion	Kidney
Identifiers
	IUPAC name (+)-(R)-3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole;
CAS Number	158747-02-5 ; succinate: 158930-17-7 ;
PubChem CID	77992;
IUPHAR/BPS	7191;
DrugBank	DB00998 ;
ChemSpider	70378 ;
UNII	H82Q2D5WA7; succinate: D28J6W18HY ;
KEGG	D07997 ;
ChEMBL	ChEMBL1279 ;
CompTox Dashboard (EPA)	DTXSID0023080 ;
Chemical and physical data
Formula	C14H17N3O
Molar mass	243.310 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN[C@@H]3CCc2[nH]c1ccc(C(N)=O)cc1c2C3;
	InChI InChI=1S/C14H17N3O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18)/t9-/m1/s1 ; Key:XPSQPHWEGNHMSK-SECBINFHSA-N ;
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Frovatriptan, sold under the brand name Frova, is a triptan medication developed by Vernalis for the treatment of migraine headaches and for short term prevention of menstrual migraine. The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe.