Edward Trifonov
Edward Nikolayevich Trifonov | |
|---|---|
אדוארד טריפונוב | |
| Born | March 31, 1937 (age 88) Leningrad, USSR |
| Nationality | Israeli |
| Alma mater | Moscow Institute of Physics and Technology |
| Known for | DNA periodicity, DNA curvature, nucleosome positioning, protein structure, molecular evolution |
| Scientific career | |
| Fields | Bioinformatics, genomics, molecular biophysics, proteomics |
| Institutions | Moscow Institute of Physics and Technology I. V. Kurchatov Institute of Atomic Energy Weizmann Institute of Science University of Haifa |
| Doctoral advisor | Yuri Semenovich Lazurkin |
| Doctoral students | Jaime Lagunez |
Edward Nikolayevich Trifonov (Hebrew: אדוארד טריפונוב, Russian: Эдуард Трифонов; b. March 31, 1937) is a Russian-born Israeli molecular biophysicist and a founder of Israeli bioinformatics. In his research, he specializes in the recognition of weak signal patterns in biological sequences and is known for his unorthodox scientific methods.
He discovered the 3-bp and 10-bp periodicity in the DNA sequences, as well as the rules determining the curvature of DNA molecules and their bending within nucleosomes. Trifonov unveiled multiple novel codes in biological sequences and the modular structure of proteins. He proposed an abiogenic theory of the origin of life, and molecular evolution from single nucleotides and amino acids to present-day DNA and protein sequences.