Dieulafoy's lesion

Dieulafoy's lesion
Other namesExulceratio simplex Dieulafoy
Blood supply of stomach
Pronunciation
  • "Do-la-foy"
SpecialtyGastroenterology
SymptomsHematemesis, melena, hematochezia, anemia
Usual onset52 years (average age)
CausesAberrant submucosal arteriole
Diagnostic methodUpper endoscopy
TreatmentEndoscopic therapy with endoclip, argon plasma coagulation, electrocautery, epinephrine injection, etc
Prognosis8% mortality
Frequency1.5% of gastrointestinal bleeding

Dieulafoy's lesion (French: [djølafwa]) is a medical condition characterized by a large tortuous artery most commonly in the stomach wall (submucosal) that erodes and bleeds. It can present in any part of the gastrointestinal tract. It can cause gastric hemorrhage but is relatively uncommon. It is thought to cause less than 5% of all gastrointestinal bleeds in adults. It was named after French surgeon Paul Georges Dieulafoy, who described this condition in his paper "Exulceratio simplex: Leçons 1-3" in 1898. It is also called "caliber-persistent artery" or "aneurysm" of gastric vessels. However, unlike most other aneurysms, these are thought to be developmental malformations rather than degenerative changes.