DPI-3290

DPI-3290
Identifiers
	IUPAC name 3-[(R)-[(2S,5R)-2,5-dimethyl-4-prop-2-enylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N-(3-fluorophenyl)-N-methylbenzamide;
CAS Number	182417-73-8 ;
PubChem CID	9826770;
ChemSpider	8002513 ;
UNII	R3UO4Y068S;
ChEMBL	ChEMBL155892 ;
Chemical and physical data
Formula	C30H34FN3O2
Molar mass	487.619 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@H]1CN([C@@H](CN1[C@@H](C2=CC(=CC=C2)O)C3=CC=CC(=C3)C(=O)N(C)C4=CC(=CC=C4)F)C)CC=C;
	InChI InChI=1S/C30H34FN3O2/c1-5-15-33-19-22(3)34(20-21(33)2)29(24-10-7-14-28(35)17-24)23-9-6-11-25(16-23)30(36)32(4)27-13-8-12-26(31)18-27/h5-14,16-18,21-22,29,35H,1,15,19-20H2,2-4H3/t21-,22+,29-/m1/s1 ; Key:LZXRQLIIMYJZDA-UETOGOEVSA-N ;
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DPI-3290 was discovered by scientists at Burroughs Wellcome and licensed to Delta Pharmaceutical and is a drug that is used in scientific research. It is a potent analgesic drug, which produces little respiratory depression.

DPI-3290 acts as an agonist at both μ- and δ-opioid receptor, with an IC50 of 6.2nM at μ and 1.0nM at δ.

Identifiers

IUPAC name 3-[(R)-[(2S,5R)-2,5-dimethyl-4-prop-2-enylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N-(3-fluorophenyl)-N-methylbenzamide
CAS Number	182417-73-8^N
PubChem CID	9826770
ChemSpider	8002513^N
UNII	R3UO4Y068S
ChEMBL	ChEMBL155892^N
Chemical and physical data
Formula	C₃₀H₃₄FN₃O₂
Molar mass	487.619 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@H]1CN([C@@H](CN1[C@@H](C2=CC(=CC=C2)O)C3=CC=CC(=C3)C(=O)N(C)C4=CC(=CC=C4)F)C)CC=C
InChI InChI=1S/C30H34FN3O2/c1-5-15-33-19-22(3)34(20-21(33)2)29(24-10-7-14-28(35)17-24)23-9-6-11-25(16-23)30(36)32(4)27-13-8-12-26(31)18-27/h5-14,16-18,21-22,29,35H,1,15,19-20H2,2-4H3/t21-,22+,29-/m1/s1^N Key:LZXRQLIIMYJZDA-UETOGOEVSA-N^N
^NY (what is this?) (verify)