Döhle bodies

Döhle bodies are light blue-gray, oval, basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils. They measure 1–3 μm in diameter. Not much is known about their formation, but they are thought to be remnants of the rough endoplasmic reticulum.

They are named after German pathologist, Karl Gottfried Paul Döhle (1855–1928). They are often present in conjunction with toxic granulation. However, it has been found that certain healthy individuals may have persistent Döhle bodies found in neutrophils.

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