Articaine

Articaine
Clinical data
Other names	Carticaine
AHFS/Drugs.com	Monograph
Routes of; administration	Subcutaneous, submucosal, parenteral, epidural, intravenous
ATC code	N01BB08 (WHO) ;
Legal status
Legal status	US: ℞-only;
Pharmacokinetic data
Metabolism	Liver, plasma
Elimination half-life	30 min
Excretion	Liver and unspecific plasma estearases
Identifiers
	IUPAC name (RS)-Methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate;
CAS Number	23964-58-1 ; HCl: 23964-57-0 ;
PubChem CID	32170;
DrugBank	DB09009 ;
ChemSpider	29837 ;
UNII	D3SQ406G9X; HCl: QS9014Q792 ;
KEGG	D07468 ;
ChEMBL	ChEMBL1093 ;
CompTox Dashboard (EPA)	DTXSID7048536 ;
ECHA InfoCard	100.115.711
Chemical and physical data
Formula	C13H20N2O3S
Molar mass	284.37 g/mol; 320.836 g/mol (HCl) g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES O=C(Nc1c(scc1C)C(=O)OC)C(NCCC)C;
	InChI InChI=1S/C13H20N2O3S/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4/h7,9,14H,5-6H2,1-4H3,(H,15,16) ; Key:QTGIAADRBBLJGA-UHFFFAOYSA-N ;
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Articaine is a dental amide-type local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries. It is the only local anaesthetic to contain a thiophene ring, meaning it can be described as 'thiophenic'; this conveys lipid solubility.