AZD-2327

AZD-2327
Clinical data
Other names	AZD 2327; AZD2327
Routes of; administration	Oral
Drug class	δ-Opioid receptor agonist
Identifiers
	IUPAC name 4-[(R)-(3-aminophenyl)-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]methyl]-N,N-diethylbenzamide;
CAS Number	875647-81-7 ; 1197281-62-1 (hemifumarate);
PubChem CID	11525765;
ChemSpider	9700551;
UNII	3Q7J827527;
ECHA InfoCard	100.170.827
Chemical and physical data
Formula	C29H35FN4O
Molar mass	474.624 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCN(CC)C(=O)C1=CC=C(C=C1)[C@H](C2=CC(=CC=C2)N)N3CCN(CC3)CC4=CC=C(C=C4)F;
	InChI InChI=1S/C29H35FN4O/c1-3-33(4-2)29(35)24-12-10-23(11-13-24)28(25-6-5-7-27(31)20-25)34-18-16-32(17-19-34)21-22-8-14-26(30)15-9-22/h5-15,20,28H,3-4,16-19,21,31H2,1-2H3/t28-/m1/s1; Key:XGFLMBBZEPJGHY-MUUNZHRXSA-N;

AZD-2327 is a δ-opioid receptor agonist which was under development for the treatment of depressive disorders and anxiety disorders but was never marketed. It is taken by mouth.

Clinical data

Other names	AZD 2327; AZD2327
Routes of administration	Oral
Drug class	δ-Opioid receptor agonist
Identifiers
IUPAC name 4-[(R)-(3-aminophenyl)-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]methyl]-N,N-diethylbenzamide
CAS Number	875647-81-7 1197281-62-1 (hemifumarate)
PubChem CID	11525765
ChemSpider	9700551
UNII	3Q7J827527
ECHA InfoCard	100.170.827
Chemical and physical data
Formula	C₂₉H₃₅FN₄O
Molar mass	474.624 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCN(CC)C(=O)C1=CC=C(C=C1)[C@H](C2=CC(=CC=C2)N)N3CCN(CC3)CC4=CC=C(C=C4)F
InChI InChI=1S/C29H35FN4O/c1-3-33(4-2)29(35)24-12-10-23(11-13-24)28(25-6-5-7-27(31)20-25)34-18-16-32(17-19-34)21-22-8-14-26(30)15-9-22/h5-15,20,28H,3-4,16-19,21,31H2,1-2H3/t28-/m1/s1 Key:XGFLMBBZEPJGHY-MUUNZHRXSA-N