ACADM

ACADM
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1EGC, 1EGD, 1EGE, 1T9G, 2A1T, 4P13
Identifiers
Aliases	ACADM, acyl-CoA dehydrogenase, C-4 to C-12 straight chain, ACAD1, MCAD, MCADH, acyl-CoA dehydrogenase medium chain
External IDs	OMIM: 607008; MGI: 87867; HomoloGene: 3; GeneCards: ACADM; OMA:ACADM - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	75,787,575 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	153,650,269 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; right ventricle; ; Skeletal muscle tissue of biceps brachii; ; body of tongue; ; vastus lateralis muscle; ; renal medulla; ; kidney tubule; ; skin of thigh;
	Top expressed in
	right ventricle; ; myocardium of ventricle; ; right kidney; ; brown adipose tissue; ; human kidney; ; soleus muscle; ; extraocular muscle; ; digastric muscle; ; cardiac muscles; ; tunica adventitia of aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity, acting on the CH-CH group of donors; acyl-CoA dehydrogenase activity; identical protein binding; oxidoreductase activity; medium-chain-acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding;
Cellular component	axon; mitochondrion; extracellular exosome; nucleus; nuclear speck; mitochondrial matrix; mitochondrial membranes;
Biological process	medium-chain fatty acid metabolic process; lipid metabolism; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid metabolic process; metabolism; carnitine biosynthetic process; medium-chain fatty acid catabolic process; carnitine metabolic process, CoA-linked; fatty acid beta-oxidation; regulation of lipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	34
	11364
	ENSG00000117054
	ENSMUSG00000062908
	P11310
	P45952
	NM_000016; NM_001127328; NM_001286042; NM_001286043; NM_001286044
	NM_007382
	NP_000007; NP_001120800; NP_001272971; NP_001272972; NP_001272973
	NP_031408
	Wikidata
View/Edit Human	View/Edit Mouse

ACADM (acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain) is a gene that provides instructions for making an enzyme called acyl-coenzyme A dehydrogenase that is important for breaking down (degrading) a certain group of fats called medium-chain fatty acids.

These fatty acids are found in foods such as milk and certain oils, and they are also stored in the body's fat tissue. Medium-chain fatty acids are also produced when larger fatty acids are degraded.

The acyl-coenzyme A dehydrogenase for medium-chain fatty acids (ACADM) enzyme is essential for converting these particular fatty acids to energy, especially during periods without food (fasting). The ACADM enzyme functions in mitochondria, the energy-producing centers within cells. It is found in the mitochondria of several types of tissues, particularly the liver.

The ACADM gene is located on the short (p) arm of chromosome 1 at position 31, from base pair 75,902,302 to base pair 75,941,203.