2022 French Open – Women's singles

Iga Świątek defeated Coco Gauff in the final, 6–1, 6–3 to win the women's singles tennis title at the 2022 French Open. It was her second French Open title and second major title overall. With the win, Świątek extended her winning streak to 35 matches (dating to the Qatar Open in February). Świątek was the youngest winner of multiple majors since Maria Sharapova in 2006.

Barbora Krejčíková was the defending champion, but lost in the first round to Diane Parry. This marked only the third time in French Open history that the defending champion lost in the first round (after Anastasia Myskina in 2005 and Jeļena Ostapenko in 2018), and the record 15th consecutive unsuccessful French Open women's singles title defense since 2007.

This was the first edition of the French Open since 2004 to feature three Americans in the quarterfinals: Gauff, Jessica Pegula, and Sloane Stephens. Gauff was the youngest major finalist since Sharapova at the 2004 Wimbledon Championships, and the youngest French Open finalist since Kim Clijsters in 2001. 17-year-old Linda Nosková was the youngest qualifier to debut in the main draw since Michelle Larcher de Brito in 2009. This marked only the second time in the Open Era when just one of the top ten seeds reached the fourth round of a major, after the 2018 Wimbledon Championships.

This marked the final French Open appearance for 2018 champion and former world No. 1 Simona Halep. She lost to Zheng Qinwen in the second round.

This was the first edition of the tournament to feature a final-set tiebreak. When the score in a final set reached 6–6, the first player to reach 10 points and lead by at least two points won the set (and the match). The first women's singles main-draw match to feature the ten-point tie break was the first-round match between Irina-Camelia Begu and Jasmine Paolini, with Begu emerging victorious.