2022 Emilia-Romagna Open – Women's singles
| Women's singles | |
|---|---|
| 2022 Emilia-Romagna Open | |
| Champion | Mayar Sherif |
| Runner-up | Maria Sakkari |
| Score | 7–5, 6–3 |
| Draw | 32 |
| Seeds | 8 |
Mayar Sherif defeated Maria Sakkari in the final, 7–5, 6–3 to win the women's singles tennis title at the 2022 Emilia-Romagna Open. It was her maiden WTA Tour title, and Sherif became the first Egyptian to win a WTA Tour singles title.
Coco Gauff was the reigning champion, but did not participate.