2022 Emilia-Romagna Open – Women's singles

Women's singles
2022 Emilia-Romagna Open
Champion Mayar Sherif
Runner-up Maria Sakkari
Score7–5, 6–3
Draw32
Seeds8

Mayar Sherif defeated Maria Sakkari in the final, 7–5, 6–3 to win the women's singles tennis title at the 2022 Emilia-Romagna Open. It was her maiden WTA Tour title, and Sherif became the first Egyptian to win a WTA Tour singles title.

Coco Gauff was the reigning champion, but did not participate.

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