2021 Australian Open – Wheelchair men's singles
| Wheelchair men's singles | |
|---|---|
| 2021 Australian Open | |
| Champion | Joachim Gérard |
| Runner-up | Alfie Hewett |
| Score | 6–0, 4–6, 6–4 |
Joachim Gérard defeated Alfie Hewett in the final, 6–0, 4–6, 6–4 to win the men's singles wheelchair tennis title at the 2021 Australian Open.
Shingo Kunieda was the defending champion, but was defeated by Hewett in the semifinals.