2021 Antalya Open – Singles
| Singles | |
|---|---|
| 2021 Antalya Open | |
| Champion | Alex de Minaur |
| Runner-up | Alexander Bublik |
| Score | 2–0 ret. |
| Draw | 32 (6 Q / 3 WC ) |
| Seeds | 8 |
Lorenzo Sonego was the defending champion, but chose not to participate. Alex de Minaur defeated Alexander Bublik in the final, 2–0, after Bublik retired with an ankle injury.