2010 Regions Morgan Keegan Championships – Singles
| Singles | |
|---|---|
| 2010 Regions Morgan Keegan Championships and the Cellular South Cup | |
| Champion | Sam Querrey |
| Runner-up | John Isner |
| Score | 6–7(3–7), 7–6(7–5), 6–3 |
| Draw | 32 |
| Seeds | 8 |
Andy Roddick was the defending champion, but lost in the quarterfinals to Sam Querrey.
Sam Querrey won in the final 6–7(3–7), 7–6(7–5), 6–3, against John Isner.