1959 U.S. National Championships – Women's singles

Women's singles
1959 U.S. National Championships
Champion Maria Bueno
Runner-up Christine Truman
Score6–1, 6–4
Draw64
Seeds8

First-seeded Maria Bueno defeated Christine Truman 6–1, 6–4 in the final to win the women's singles tennis title at the 1959 U.S. National Championships.

This was notably the first grand slam that former world number 1 and 12 time grand slam champion Billie Jean King competed in.