17β-Dihydroequilin

17β-Dihydroequilin
Clinical data
Other names	β-Dihydroequilin; Δ7-17β-Estradiol; 7-Dehydro-17β-estradiol; Estra-1,3,5(10),7-tetraen-3,17β-diol; NSC-12170
Routes of; administration	By mouth
Drug class	Estrogen
Identifiers
	IUPAC name (9S,13S,14S,17S)-13-Methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol;
CAS Number	3563-27-7;
PubChem CID	11954027;
ChemSpider	10128322;
UNII	WXG88DST4R;
ChEBI	CHEBI:62851;
ChEMBL	ChEMBL121458;
CompTox Dashboard (EPA)	DTXSID40871892 ;
ECHA InfoCard	100.020.576
Chemical and physical data
Formula	C18H22O2
Molar mass	270.372 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CC[C@H]3C(=CCC4=C3C=CC(=C4)O)[C@@H]1CC[C@@H]2O;
	InChI InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16-17,19-20H,2,6-9H2,1H3/t14-,16+,17+,18+/m1/s1; Key:NLLMJANWPUQQTA-UBDQQSCGSA-N;

17β-Dihydroequilin is a naturally occurring estrogen sex hormone found in horses as well as a medication. As the C3 sulfate ester sodium salt, it is a minor constituent (1.7%) of conjugated estrogens (CEEs; brand name Premarin). However, as equilin, with equilin sulfate being a major component of CEEs, is transformed into 17β-dihydroequilin in the body, analogously to the conversion of estrone into estradiol, 17β-dihydroequilin is, along with estradiol, the most important estrogen responsible for the effects of CEEs.

Clinical data

Other names	β-Dihydroequilin; Δ⁷-17β-Estradiol; 7-Dehydro-17β-estradiol; Estra-1,3,5(10),7-tetraen-3,17β-diol; NSC-12170
Routes of administration	By mouth
Drug class	Estrogen
Identifiers
IUPAC name (9S,13S,14S,17S)-13-Methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol
CAS Number	3563-27-7
PubChem CID	11954027
ChemSpider	10128322
UNII	WXG88DST4R
ChEBI	CHEBI:62851
ChEMBL	ChEMBL121458
CompTox Dashboard (EPA)	DTXSID40871892
ECHA InfoCard	100.020.576
Chemical and physical data
Formula	C₁₈H₂₂O₂
Molar mass	270.372 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@]12CC[C@H]3C(=CCC4=C3C=CC(=C4)O)[C@@H]1CC[C@@H]2O
InChI InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16-17,19-20H,2,6-9H2,1H3/t14-,16+,17+,18+/m1/s1 Key:NLLMJANWPUQQTA-UBDQQSCGSA-N