Hydroxybenzotriazole

Hydroxybenzotriazole
Names
	Preferred IUPAC name 1H-1,2,3-Benzotriazol-1-ol
	Other names N-Hydroxybenzotriazole; HOBt
Identifiers
CAS Number	2592-95-2 ; (monohydrate): 80029-43-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	68282 ;
ECHA InfoCard	100.018.173
EC Number	219-989-7; (monohydrate): 602-929-2;
PubChem CID	75771; (monohydrate): 2796029;
UNII	A2T929DMG4 ; (monohydrate): S72K7GY45F ;
CompTox Dashboard (EPA)	DTXSID3044627 ;
	InChI InChI=1S/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H Key: ASOKPJOREAFHNY-UHFFFAOYSA-N ; InChI=1/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H Key: ASOKPJOREAFHNY-UHFFFAOYAP;
	SMILES n1nn(O)c2ccccc12;
Properties
Chemical formula	C6H5N3O
Molar mass	135.1234 g mol−1 (anhydrous)
Melting point	156 to 159 °C (313 to 318 °F; 429 to 432 K) (decomposes)
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H203
Precautionary statements	P210, P230, P240, P250, P280, P370+P380, P372, P373, P401, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Hydroxybenzotriazole (abbreviated HOBt) is an organic compound with the formula C₆H₄N₃OH. It is a derivative of benzotriazole. It is a white crystalline powder, which as a commercial product contains some water (~11.7% wt as the HOBt monohydrate crystal). Anhydrous HOBt is explosive. It is mainly used to suppress the racemization and to improve the efficiency of peptide synthesis.

Names


Preferred IUPAC name 1H-1,2,3-Benzotriazol-1-ol
Other names N-Hydroxybenzotriazole HOBt
Identifiers
CAS Number	2592-95-2^Y (monohydrate): 80029-43-2^Y
3D model (JSmol)	Interactive image
ChemSpider	68282^Y
ECHA InfoCard	100.018.173
EC Number	219-989-7 (monohydrate): 602-929-2
PubChem CID	75771 (monohydrate): 2796029
UNII	A2T929DMG4^Y (monohydrate): S72K7GY45F^Y
CompTox Dashboard (EPA)	DTXSID3044627
InChI InChI=1S/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H^Y Key: ASOKPJOREAFHNY-UHFFFAOYSA-N^N InChI=1/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H Key: ASOKPJOREAFHNY-UHFFFAOYAP
SMILES n1nn(O)c2ccccc12
Properties
Chemical formula	C₆H₅N₃O
Molar mass	135.1234 g mol⁻¹ (anhydrous)
Melting point	156 to 159 °C (313 to 318 °F; 429 to 432 K) (decomposes)
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H203
Precautionary statements	P210, P230, P240, P250, P280, P370+P380, P372, P373, P401, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references